Programme

GENFI Summer Meeting 2025 Programme

Venue:
Scholastika Haus: https://scholastika.de/#location

Zoom link

Thursday, June 5th

11.00-11.30
Welcome and meet with investigators over coffee

11.30-12.00
Welcome to Munich
Johannes Levin, Adrian Danek, Günter Höglinger, Matthis Synofzik

12.00-12.30
Initial update on recruitment, data freezes and publications
Jonathan Rohrer, Phoebe Foster, Sophie Farley and Eve Ferry-Bolder

12.30-12.50
New sites introduction - 5 minute flash talks
Chair - Sophie Farley

12.50-2.00
Update on clinical, cognitive and digital projects
Chair - Lena Marth

12.50 Survival in genetic FTD - Barbara Borroni/Arabella Bouzigues
1.00 Update on Ignite - Rhian Convery
1.10 Autonomic symptoms in genetic FTD - Sonja Schönecker
1.20 Network analyses of cognition - Lize Jiskoot
1.30 Measuring apathy using the b-DAS - Sophie Farley
1.40 The LISET eye tracking task - Liset de Boer
1.50 Update on cognitive impairment in young C9orf72 expansion carriers - Phoebe Foster

2.00-3.00 Lunch

3.00-4.00
Update on biomarker and genetics projects
Chair - Julie de Houwer

3.00 Serum Sphingolipid and Phospholipid level alterations in GRN-mediated FTD - Gabriel Miltenberger Miltényi
3.10 The GFAP/NfL ratio in genetic FTD - Julie de Houwer
3.20 TMEM106B as a genetic modulator of GRN disease: an explainable machine learning study - Enrico Premi
3.30 Results of Gal3 as a biomarker of FTD due MAPT mutations - Sergi Borrego
3.40 Beta-synuclein measurements in the GENFI cohort - Markus Otto
3.50 Update on genomics and epigenomics - Mario Masellis
4.00 Cross-sectional and longitudinal effects of rare genetic variants on cortical and subcortical grey matter volumes in genetic FTD - Saira Mirza

4.10-4.40 Coffee

4.40-5.20
Update on imaging projects
Chair - Laura Göschel
4.40 Plasma protein profiling and structural MRI - Abbe Ullgren
4.50 GRN/C9orf72 structural and functional connectivity - Arabella Bouzigues
5.00 Longitudinal DWI in GENFI - Elena Rodriguez-Vieitez
5.10 Longitudinal functional connectivity in the GENFI cohort - Maurice Pasternak

5.20-5.30
Update on therapeutics
Chair - Sonja Schönecker
5.20 Development of a C9 vaccine - Dieter Edbauer

5.30 Finish

7.00 Drinks and dinner
Hofbräuhaus - www.hofbraeuhaus.de
sponsored by the Bluefield Project

Friday, 6th June

GENFI Investigators Only

9.00-9.30
Update on GENFI 3
Jonathan Rohrer, Eve Ferry-Bolder and Eva Cullen

9.30-10.30
Plans for GENFI 4 ALL
Jonathan Rohrer, Eve Ferry-Bolder, Amelia Blesius, and Rhian Convery

10.30-11.00 Coffee

1.00-12.00
Working groups update
11.00 Digital: Rhian Convery, Jackie Poos
11.15 Language: Rose Bruffaerts, Rosie Coppieters, Lize Jiskoot, Arabella Bouzigues
11.30 Clinical Genetics: Caroline Graff, Gabriel Miltenberger Milenyi
11.45 Diversity - Jackie Poos, Carmela Tartaglia

12.00-12.15
GENFI-NeuroDev: Elizabeth Finger

12.15-12.35
Trials and therapies working group update Jonathan Rohrer

12.35-12.55
Participant Engagement Board - Feedback from the 2nd Annual Spring Webinar
Sophie Goldsmith, Phoebe Foster

12.55-1.00
Summary of the day and plans for the future

1.00
Finish and lunch for those who can stay