Programm, 02. März 2023

1. Live Pancreatic Endoscopy
Julia Mayerle, Ch. Schulz

2. Live Pancreatic Surgery
Bernhard Renz

3. Introduction to IHC-Multiplexing and semi-automated histocytometry
UM Mahaja, D. Saka

4. Introduction to translational animal models of pancreatic diseases
A. Alnatsha, P. Prince, S. Sirtl

14:15 - 14:30 Neuro-inflammatory crosstalk in pancreatic cancer: driver or bystander? - Carmen Mota Reyes, TU Munich

14:30 - 14:45 Integrated mulit-omics immune landscape of pancreatic cancer -
Susanne Roth, UK Heidelberg

14:45 - 15:45 Oral Abstract Presentations

1. Loss of ATM facilitates nutrient stress-induced metabolic reprogramming supporting pancreatic cancer aggressiveness - Anna Härle, UK Ulm

2. Pancreatic cancer cells are addicted to expression of the PLAC8 mRNA, but not the encoded protein, for maintenance of genome integrity and cell viability - Malte Buchholz, Uni Marbur

3. Characterization of Epigenetic Modulation in Pancreatic Neuroendocrine Neoplasms - Julia Weissbach, UK Halle

4. The influence of adrenergic signaling in pancreatic cancer cell migration and invasion - Mathilda Marie Knoblauch, LMU Munich

5. Friend or foe? Delineating the role of STAT3 in pancreatic cancer aggressiveness - Samuel Rebeccadiya, Uni Göttingen

6. Characterizing the impact of MAZ in regulating inflammatory- and tumor-promoting gene programs in ARID1A-deficient PDAC subtypes - Maria Ulisse, Uni Göttingen

Each presentation takes 8 minutes plus 2 minutes of discussion.

17:00 - 17:10 Werner-Creutzfeldt-Scholarship 2021 - DPC-134: Identification of the Neurokinin-1 Receptor as Targetable Oncologic Stratification Factor for Drug Repurposing -
Iris Beirith, LMU Munich

17:10 - 17:40 Oral Abstract Presentations

1. Tumor-mircoenvironmental implications of targeted SHP2-inhibition +/- MAPK-inhibition in pancreatic cancer - Steffen Keller, Uniklinik Freiburg

2. Deciphering epithelial-to-mesenchymal plasticity driven phenotypic heterogeneity and treatment resistance utilizing primary murine and human branching pancreatic tumour organoids - Aristeidis Papargyriou, TU Munich

3. mTORC1 promotes the formation of immunosuppressive microenvironment in pancreatic ductal adenocarcinoma - Chao Fang, UKM Ulm

17:45 - 17:55 Introduction to Pancreatic Cancer Treatment - Volker Heinemann, CCC Munich

17:55 - 18:15 Finding the needle in the haystack – access is key - Benedikt Westphalen, LMU Munich

18:15 - 18:35 Personalizing Cancer Treatment in the real world - Kerstin Wolff, UK Erlangen

18:35 - 18:45 Summary and Discussion